HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Mul, D Articles by Hughes, I A Search for Related Content PubMed PubMed Citation Articles by Mul, D Articles by Hughes, I A

The use of GnRH agonists in precocious puberty

Department of Pediatrics, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands¹ Department of Paediatrics, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK

(Correspondence should be addressed to EGAH van Mil at Department of Paediatrics, Jheronimus Bosch Medical Centre, PO Box 90153, 5200 ME, s'Hertogenbosch, The Netherlands; Email: vanmil{at}jbz.nl)

This paper was presented at the 5th Ferring International Paediatric Endocrinology Symposium, Baveno, Italy (2008). Ferring Pharmaceuticals has supported the publication of these proceedings.

In this review several aspects of gonadotrophin releasing hormone agonists (GnRHa) treatment in central precocious puberty (CPP) are highlighed. These include issues of the definition of precocity, assessment of CPP and thelarche variants. Indications for treatment with GnRH agonists are discussed, not only in CPP but also in children with other reasons to suppress central activation, e.g. adopted or developmental retardation. Finally, outcome data are summarized, both on growth and psychosocial parameters.