HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Löndahl, M. Articles by Katzman, P. PubMed PubMed Citation Articles by Löndahl, M. Articles by Katzman, P.

A case of constrictive pericarditis during cabergoline treatment for hyperprolactinaemia.

Department of Endocrinology, Lund University Hospital, S-221 85 Lund, Sweden¹ Department of Internal Medicine, Angelholm Hospital, Angelholm, Sweden² Department of Radiology, Helsingborg Hospital, Helsingborg, Sweden

(Correspondence should be addressed to M Löndahl; Email: magnus.londahl{at}skane.se)

Abstract

Objective: Treatment with dopamine agonists has been associated with cardiopulmonary fibrotic reactions, predominantly in patients treated for Parkinson's disease. To our knowledge, these reactions have previously not been associated with low-dose cabergoline treatment for hyperprolactinaemia.

Method: A case of constrictive pericarditis in a patient treated with cabergoline for hyperprolactinaemia is presented. The patient has been treated at a county hospital and a university hospital in southern Sweden.

Results: A 20-year-old woman with a 3-year history of amenorrhoea was referred to the department in 1992. From 2001 to 2005, she was given cabergoline, 0.5–1.5 mg/week. In 2005 a pericardectomy was performed due to fibrotic, constrictive pericarditis.

Conclusions: Our present case suggests that constrictive pericarditis may develop even on low-dose cabergoline, which might indicate that this reaction, as opposed to valvular fibrosis, is not mediated by a 5-HT_2B agonistic mechanism.