Eur J Endocrinol
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

DOI: 10.1530/eje.0.1470561
European Journal of Endocrinology, Vol 147, Issue 5, 561-569
Copyright © 2002 by European Society of Endocrinology
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Polychronakos, C
Right arrow Articles by Kukuvitis, A
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Polychronakos, C
Right arrow Articles by Kukuvitis, A
Articles

Parental genomic imprinting in endocrinopathies

C Polychronakos and A Kukuvitis

Division of Endocrinology, Department of Pediatrics, McGill University, Montreal, Quebec, Canada. constantin.polychronakos@mcgill.ca

Genomic imprinting is the phenomenon whereby some genes preferentially produce mRNA transcripts from the gene copy derived from the parent of a specific sex. It has been implicated in a number of human diseases (most of them of endocrine interest), such as Prader-Willi/Angelman syndromes, Silver-Russell syndrome, Beckwith-Wiedemann syndrome, transient neonatal diabetes, the focal form of nesidioblastosis, and pseudohypoparathyroidism. Involvement of imprinted genes affecting birth weight and causing susceptibility to type 1 diabetes is under investigation. Recent knowledge about the varied molecular mechanisms involved will be outlined.


This article has been cited by other articles:


Home page
 Mult SclerHome page
B. Herrera, M. Cader, D. Dyment, J. Bell, G. DeLuca, C. Willer, M. Lincoln, S. Ramagopalan, M. Chao, S-M. Orton, et al.
Multiple sclerosis susceptibility and the X chromosome
Multiple Sclerosis, August 1, 2007; 13(7): 856 - 864.
[Abstract] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
G. Mantovani, S. Bondioni, M. Locatelli, C. Pedroni, A. G. Lania, E. Ferrante, M. Filopanti, P. Beck-Peccoz, and A. Spada
Biallelic Expression of the Gs{alpha} Gene in Human Bone and Adipose Tissue
J. Clin. Endocrinol. Metab., December 1, 2004; 89(12): 6316 - 6319.
[Abstract] [Full Text] [PDF]

Home page
 J. Clin. Endocrinol. Metab.Home page
G. Mantovani, M. Maghnie, G. Weber, E. De Menis, V. Brunelli, M. Cappa, P. Loli, P. Beck-Peccoz, and A. Spada
Growth Hormone-Releasing Hormone Resistance in Pseudohypoparathyroidism Type Ia: New Evidence for Imprinting of the Gs{alpha} Gene
J. Clin. Endocrinol. Metab., September 1, 2003; 88(9): 4070 - 4074.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2002 European Society of Endocrinology.