| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Huhtaniemi I. Fetal testis—a very special endocrine organ. Eur J Endocrinol 1994;130:25–31. ISSN 0804–4643
The fetal testis is a special organ endocrinologically and not at all like a smaller version of the adult testis. Unlike the quiescent fetal ovary, its hormone production is very active. Besides testosterone it produces a special 'fetal gonadal hormone', the anti-Müllerian hormone. These two hormones together play a key role in the induction and regulation of male sexual differentiation. To meet these functional requirements the fetal testis has many unique features, especially as regards luteinizing hormone and follicle-stimulating hormone action, which discriminate it from the respective functions of the adult testis. In this article, some enigmatic features of fetal testicular endocrine function are concentrated on in an attempt to identify the most important questions for further research.
Ilpo Huhtaniemi, Department of Physiology, University of Turku, Kiinamyllynkatu 10,20520 Turku, Finland
This article has been cited by other articles:
|
|
 |
|
  J. Tomaszewski, A. Joseph, D. Archambeault, and H. H.-C. Yao Essential roles of inhibin beta A in mouse epididymal coiling PNAS, July 3, 2007; 104(27): 11322 - 11327. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Welsh, P. T. K. Saunders, and R. M. Sharpe The Critical Time Window for Androgen-Dependent Development of the Wolffian Duct in the Rat Endocrinology, July 1, 2007; 148(7): 3185 - 3195. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. R. Blystone, C. S. Lambright, K. L. Howdeshell, J. Furr, R. M. Sternberg, B. C. Butterworth, E. J. Durhan, E. A. Makynen, G. T. Ankley, V. S. Wilson, et al. Sensitivity of Fetal Rat Testicular Steroidogenesis to Maternal Prochloraz Exposure and the Underlying Mechanism of Inhibition Toxicol. Sci., June 1, 2007; 97(2): 512 - 519. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Welsh, P. T. K. Saunders, N. I. Marchetti, and R. M. Sharpe Androgen-Dependent Mechanisms of Wolffian Duct Development and Their Perturbation by Flutamide Endocrinology, October 1, 2006; 147(10): 4820 - 4830. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F.-p. Zhang, T. Pakarainen, F. Zhu, M. Poutanen, and I. Huhtaniemi Molecular Characterization of Postnatal Development of Testicular Steroidogenesis in Luteinizing Hormone Receptor Knockout Mice Endocrinology, March 1, 2004; 145(3): 1453 - 1463. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.L. Barreiro, F. Gaytan, J.E. Caminos, L. Pinilla, F.F. Casanueva, E. Aguilar, C. Dieguez, and M. Tena-Sempere Cellular Location and Hormonal Regulation of Ghrelin Expression in Rat Testis Biol Reprod, December 1, 2002; 67(6): 1768 - 1776. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Pakarinen, S. Kimura, F. El-Gehani, L. J. Pelliniemi, and I. Huhtaniemi Pituitary Hormones Are Not Required for Sexual Differentiation of Male Mice: Phenotype of the T/ebp/Nkx2.1 Null Mutant Mice Endocrinology, November 1, 2002; 143(11): 4477 - 4482. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. Sharpe, B. Martin, K. Morris, I. Greig, C. McKinnell, A. S. McNeilly, and M. Walker Infant feeding with soy formula milk: effects on the testis and on blood testosterone levels in marmoset monkeys during the period of neonatal testicular activity Hum. Reprod., July 1, 2002; 17(7): 1692 - 1703. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Ginther, A. A. Carlson, T. E. Ziegler, and C. T. Snowdon Neonatal and Pubertal Development in Males of a Cooperatively Breeding Primate, the Cotton-Top Tamarin (Saguinus oedipus oedipus) Biol Reprod, February 1, 2002; 66(2): 282 - 290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. A. Hughes Minireview: Sex Differentiation Endocrinology, August 1, 2001; 142(8): 3281 - 3287. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F.-P. Zhang, M. Poutanen, J. Wilbertz, and I. Huhtaniemi Normal Prenatal but Arrested Postnatal Sexual Development of Luteinizing Hormone Receptor Knockout (LuRKO) Mice Mol. Endocrinol., January 1, 2001; 15(1): 172 - 183. [Abstract] [Full Text]
|
|
|
|
|
|
Z. M. Lei, S. Mishra, W. Zou, B. Xu, M. Foltz, X. Li, and Ch. V. Rao Targeted Disruption of Luteinizing Hormone/Human Chorionic Gonadotropin Receptor Gene Mol. Endocrinol., January 1, 2001; 15(1): 184 - 200. [Abstract] [Full Text]
|
|
|
|
 |
|
 A. P. N. Themmen and I. T. Huhtaniemi Mutations of Gonadotropins and Gonadotropin Receptors: Elucidating the Physiology and Pathophysiology of Pituitary-Gonadal Function Endocr. Rev., October 1, 2000; 21(5): 551 - 583. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. C. Zenteno, P. Canto, S. Kofman-Alfaro, and J. P. Mendez Evidence for Genetic Heterogeneity in Male Pseudohermaphroditism due to Leydig Cell Hypoplasia J. Clin. Endocrinol. Metab., October 1, 1999; 84(10): 3803 - 3806. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Tena-Sempere, A. Rannikko, J. Kero, F.-P. Zhang, and I. T. Huhtaniemi Molecular Mechanisms of Reappearance of Luteinizing Hormone Receptor Expression and Function in Rat Testis after Selective Leydig Cell Destruction by Ethylene Dimethane Sulfonate Endocrinology, August 1, 1997; 138(8): 3340 - 3348. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
