HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ahuja, S. Articles by Ernst, H. Search for Related Content PubMed PubMed Citation Articles by Ahuja, S. Articles by Ernst, H.

Hyperthyroidism and thyroid carcinoma

Twenty-two of 251 patients with differentiated thyroid carcinoma suffered from or had a history of hyperthyroidism. They were hyperthyroid with a diffuse goitre (N=4), a diffuse goitre with a cold nodule (N= 10), a multinodular goitre (N=6), and an autonomous adenoma (N=2). Among the 22 patients, more than one fourth had an occult thyroid carcinoma with a diameter of 1 cm or less, those with the papillary tumour types, less frequently had lymph node metastases than the total group of patients with papillary carcinomas (13.3 vs 35.6%). The clinical courses of the 22 patients resembled those of the other thyroid carcinoma patients whose age and initial findings were comparable. In 643 patients who underwent surgery for hyperthyroidism the incidence of thyroid carcinoma was 2.3%. The increase in coincidence of hyperthyroidism and thyroid carcinoma repeatedly reported in recent years is probably ascribable primarily to extensive and improved diagnostics and not to a direct connection between hyperthyroidism and development of thyroid carcinoma. On the other hand, our findings do confirm that, even in the presence of hyperthyroidism, all thyroid nodules require careful diagnostics for exclusion of malignancy.

This article has been cited by other articles:

				K. Pazaitou-Panayiotou, P. Perros, M. Boudina, G. Siardos, A. Drimonitis, F. Patakiouta, and I. Vainas Mortality from thyroid cancer in patients with hyperthyroidism: the Theagenion Cancer Hospital experience Eur. J. Endocrinol., December 1, 2008; 159(6): 799 - 803. [Abstract] [Full Text] [PDF]

				L. R. Petrone A Primary Care Approach to the Adult Patient With Nodular Thyroid Disease Arch Fam Med, February 1, 1996; 5(2): 92 - 100. [Abstract] [PDF]